Orofacial dysfunctions are present in all ages and relate to several diagnoses, both congenital and acquired. Any dysfunction in the area of the face and mouth can have great impact on important body functions and may negatively affect quality of life. In case of orofacial dysfunction, oral health is also at risk. Thus, all professionals in the dental team should have sufficient knowledge about orofacial function and strategies on how to best care for this group of patients, throughout the whole life span. Young children with eating disorders, adolescents with myofunctional disorders and geriatric patients with reduced oral clearance – they all need care from a multi-professional team. In this seminar, we will cover a spectrum of disorders with emphasis on questions related to orofacial function. The presenters come from different parts of the world and together they represent a multi-professional dental team.